MỐI LIÊN QUAN GIỮA LOÃNG XƯƠNG VÀ THOÁI HÓA KHỚP GỐI Ở PHỤ NỮ CAO TUỔI

Vân Đinh Phạm Thị Thúy; Trang Phạm Ngọc Thùy; Công Nguyễn Đức; Trí Nguyễn Văn

doi:10.59354/ydth175.2021.104

Keywords:

Osteoporosis, osteoarthritis

Abstract

Objective: Investigating the association between osteoporosis and knee osteoarthritis in the elderly women.

Method: A cross-sectional study was conducted with the participation of 200 elderly women patients (≥ 60 years of age). Knee osteoarthritis was diagnosed according to American College of Rheumatology criteria in 1986 and the radiographic severity at knee joints was determined by the Kellgren Lawrence grading system. Osteoporosis was diagnosed based on World Health Organization’criteria in 1994 by measuring bone mineral density assessed by dual-energy X-ray absorptiometry.

Results: The prevalence of osteoporosis in the group with osteoarthritis was lower than in the group without osteoarthritis (40,3% versus 55,26%), the difference was statistically significant. (p = 0,04). Overall, patient with osteoporosis reduce osteoarthritis risk by 58% (OR = 0,42; 95% CI [0,2 - 0,83], p = 0,013). However, analyzing subgroups of the Kellgren Lawrence on knee radiographs found that the prevalence of osteoporosis in the Kellgren Lawrence 3 – 4 (moderate to severe knee osteoarthritis) was higher than in the Kellgren Lawrence 1 – 2 (mild knee osteoarthritis) (56,5% versus 39%) with statistically significant difference (p = 0,037).

Conclusion: The elderly women patients with mild knee osteoarthritis have a lower prevalence of osteoporosis. However, the prevalence of osteoporosis increases in severe knee osteoarthritis.

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