NHÂN TRƯỜNG HỢP ĐIỀU TRỊ U TUYẾN TUYẾN YÊN KHÔNG TĂNG TIẾT CÓ HẠ NATRI MÁU NẶNG VÀ ĐÁI THÁO NHẠT TRUNG ƯƠNG

Trung Thông Hoàng; Quốc Nam Phạm; Đặng Phương Kiều Nguyễn

doi:10.59354/ydth175.2022.16

Keywords:

Nonfunctioning pituitary adenomas, hypopituitarism, severe hyponatremia, central diabetes insipidus

Abstract

Nonfunctioning pituitary adenomas (NFPAs) are the most benign neoplasms that arise from the adenohypophyseal cells without clinical or biochemical evidence of hormone excess. The prevalence of NFPAs is uncommon and many NFPAs are undiagnosed until they are very large and cause mass effect or are accidentally discovered. It also causes many complications. Macroadenomas result in obstruction of the portal vein system of the hypothalamus and pituitary gland, also compress normal pituitary tissue that are the pathophysiology of hypopituitarism and central diabetes insipidus. However, severe hyponatremia because of hypopituitarism and central diabetes insipidus are two rare clinical symptoms in NFPAs. This case report represents a 62 – year - old male patient with NFPA involving hypopituitarism, severe hyponatremia, central diabetes insipidus and spontaneous regression after 6 months monitoring.

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