ASSESSMENT OF POSTOPERATIVE COGNITIVE DYSFUNTION IN THE ELDERLY AFTER SPINAL ANESTHESIA FOR HIP AND KNEE JOINT ARTHROPLASTY


Authors

  • Khánh Bùi Quốc Bệnh viện Quân y 175
  • Trí Bùi Quang Bệnh viện Quân y 175
  • Dung Nguyễn Bệnh viện Quân y 175
  • Bình Trần Bệnh viện Quân y 175
  • Thành Bùi Đức Bệnh viện Quân y 175
DOI: https://doi.org/10.59354/ydth175.2024.241

Keywords:

Postoperative cognitive dysfunction, elderly people

Abstract

Background: Postoperative cognitive dysfunction in the elderly greatly affects the quality of recovery after surgery. Our research question is: “What is the rate of postoperative cognitive dysfunction in the elderly after spinal anesthesia for hip and knee joint arthroplasty in postoperative 5 days?”

Materials and Methods: Elderly patients (≥ 60 years) receiving spinal anesthesia for joint arthroplasty. Design of this study is longitudinal observational, prospective, single-center.

Results: 22,5% of elderly patients had postoperative cognitive dysfunction for joint arthroplasty and received spinal anesthesia in the first 5 days of surgery. Multivariable Cox regression analysis had 3 risk factors: use of sedative midazolam during surgery (p = 0,002); perioperative blood transfusion of more than 2 units of red blood cells (p = 0,01) and moderate pain level on day 1 (p = 0,008).

Conclusions: Of all the 107 patients, 24 (22,5%) developed postoperative cognitive dysfunction in postoperative 5 days, occurring on medium 2 days after surgery. There are 3 risk factors for postoperative cognitive dysfunction: the use of sedative midazolam during surgery, perioperative blood transfusion of more than 2 units of red blood cells and moderate pain level on day 1.

References

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Li WX, Luo RY, Chen C, et al. Effects of propofol, dexmedetomidine, and midazolam on postoperative cognitive dysfunction in elderly patients: a randomized controlled preliminary trial. Chin Med J (Engl). Feb 2019;132(4):437-445.

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Published

06-05-2024

How to Cite

Bùi Quốc , K., Bùi Quang , T., Nguyễn , D., Trần , B., & Bùi Đức , T. (2024). ASSESSMENT OF POSTOPERATIVE COGNITIVE DYSFUNTION IN THE ELDERLY AFTER SPINAL ANESTHESIA FOR HIP AND KNEE JOINT ARTHROPLASTY. Journal of 175 Practical Medicine and Pharmacy, (37), 9. https://doi.org/10.59354/ydth175.2024.241