NHẬN XÉT KẾT QUẢ CỦA LỌC MÁU KẾT HỢP THẬN NHÂN TẠO VÀ QUẢ LỌC MÁU HẤP PHỤ HA130 TRÊN BỆNH NHÂN CHẠY THẬN NHÂN TẠO ĐỊNH KỲ

Phú Quốc Nguyễn

doi:10.59354/ydth175.2022.53

Keywords:

Chronic kidney disease, hemodialysis, hemoperfusion

Abstract

Objectives: Evaluate some advantages of the combination of hemodialysis (HD) and hemoperfusion (HP) by using HA130 cartridge to hemodialysis; and investigate some disorders of the combination of hemodialysis and hemoperfusion in chronic kidney disease patients with hemodialysis.

Materials and methods: From 2019 to 2020, a prospective study that was going on patients receiving hemodialysis with HA130 cartridge once a week in combination with 2 times a week hemodialysis alone for 3 weeks. These patients will be checked for clinical and laboratory parameters before and after dialysis (HD+HP), we will record the results and put them in the data analysis table.

Results: There were 10 eligible patients included in the study. In which, there was no clinical difference before and after HD+HP. In addition, the combination of HD+HP by using HA130 cartridge was significantly showed a lot of beneficial results, such as: lowering Parathyroid hormone (PTH) (1129 pmol/l → 655 pmol/l) (P < 0,001); lowering Acid uric (464 mmol/l → 201 mmol/l) (P < 0,001); lowering Phospho (1,99 mmol/l → 1,26 mmol/l) (P < 0,001), lowering Ure (25,68 mmol/l → 8,57 mmol/l) (P < 0,001); lowering Creatinin (901 μmol/l → 379 μmol/l) (P < 0,001).

Conclusion: The combination of HD+HP with HA130 cartridge brings many benefits and no serious adverse incidents occurred during the HD+HP treatment.

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