XÁC ĐỊNH GIÁ TRỊ TIÊN LƯỢNG TỬ VONG CỦA CYTOKINE STORM SCORE (CSs) Ở BỆNH NHÂN COVID – 19 NHẬP VIỆN ĐIỀU TRỊ TẠI BỆNH VIỆN QUÂN Y 175

Minh Thế Nguyễn; Thị Thơm Trần; Gia Hiệp Nguyễn; Công Trường Nguyễn; Hải Công Nguyễn

doi:10.59354/ydth175.2022.55

Keywords:

COVID – 19, CSs, cytokine storm score, mortality prognosis

Abstract

Objective: Determine prognostic value of Cytokine Storm Score (CSs) in hospitalized COVID-19 patients.

Materials and Methods: Prospective study, longitudinal follow-up of 81 COVID-19 patients admitted to the COVID-19 treatment center, Military Hospital 175 from August 2021 to October 2021. CSs and CURB - 65 score were used to assess the risk of death when patients are hospitalized for treatment.

Results:81 COVID-19 patients were studied, the mean age was 55.67 ± 14.6. Male patients were 45.7% and female patients were54.3%. There were 44 CSs positive patients, accounting for 54.32%. The higher the conventional CSs score in the more severe COVID-19 patients, the statistically significant difference, p< 0.001. The conventional CSs scale has a good predictive ability of mortality in COVID-19 patients, with an area under the ROC curve of 0.95. The cut-off point with the best predictive value for mortality is CSs ≥ 4 points, with sensitivity 96.55%, specificity 82.69%, positive predictive value 75.67%, negative predictive value 97.72%.

Conclusion: The conventional CSs is an effective tool to predict the risk of death for hospitalized COVID-19 patients.

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Bộ y tế, Hướng dẫn chẩn đoán và điều trị COVID-19 do chủng vi rút Corona mới (SARS-CoV-2) theo Quyết định 3416/QĐ-BYT ngày 14/7/2021

Bộ y tế Cổng thông tin của Bộ Y tế về đại dịch Covid-19 - covid19.gov. vn.

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